Efavir (Efavirenz) provides highly effective control and treatment of HIV-1 (human immunodeficiency virus) infections. However, it is only used with other anti-retroviral drugs and not on its own. This is because monotherapy with this medicine allows the virus to become rapidly resistant to it, which can make treatment difficult. It is classified as a non-nucleoside reverse transcriptase inhibitor, and its pharmacological action involves diffusing in the cells and attaching to the HIV enzyme responsible for the recreation of viral DNA (reverse transcriptase). It inhibits this enzyme in a non-competitive manner, and this stops the virus from spreading. Other drugs are added to the treatment, and this is known as highly active antiretroviral therapy. When used as directed by a physician, it can reduce HIV blood levels and prevent illnesses.
- Concentration difficulties
Your physician will regularly conduct various medical assessments so that your condition can be monitored. All side effects (no matter how mild) must be thoroughly reported. Rarely, serious reactions will occur. Should you experience bloody urine, abnormal behavioral disturbances, significant appetite reduction, speech problems, unexplained weigh increases or any other severe side effects, see your physician immediately.
Liver function tests will be a requirement for the entire duration of treatment with this medicine. Your physician may also need to check you regularly for signs of other serious conditions, such as osteonecrosis.